Agent E is a bald eagle which works for The O.W.C.A. Her base is supposedly located near where Phineas's Grandparents live, as this is where her nest is located and the only place we see her. She made her debut in the episode "The Ballad of Badbeard".
Agent E came soaring down after Agent P is unable to open up one of the secret passageways to his lair located in the area. She took Agent P to her nest where Major Monogram communicates to Agent P through a small TV hidden in one of her eggs. Agent E then sprayed worms into her nest, indicating that she is expecting the other eggs to hatch soon. She then dropped Agent P off at the docks and isn't seen from again until near the end of the episode, where she swoops down and rescues Agent P and Candace, although she may not have realized this from Heinz Doofenshmirtz island, which had been set to self destruct.Like most Agents in the series, the first name of Agent E is never mentioned. She is also one of the only Agents in the series so far that we can presume is female. The other being Agent C. Although, Agent E could possibly be male, with those other eggs just concealing more technology.